Following the events of her bombshell announcement, the fifth season begins as Nancy digs deeper into the drug world and finds comfort in an unlikely family member.
Nancy pays the imprisoned Guillermo a secret visit and Shane leaves to live with Nancy's sister. In the meantime, Silas and Doug have difficulties growing pot in a national forest.
Jill pays Nancy a surprise visit. Meanwhile, Celia gets sent back to the U.S., Nancy's bodyguard is missing and Silas and Doug look for law enforcement authorization.
Nancy is visited by DEA agent Roy Till who has gone rogue and homecomer Celia moves into Nancy's garage. Meanwhile, Andy tries to access his brother's old bank account.
Nancy talks with her obstetrician about ending the pregnancy. After his teacher took his pot, Shane needs some help to get it back. Andy is still trying to get access to his late brother's bank account. Meanwhile, Silas and Doug need to see "The Wizard" to make their pot selling dreams come true.
A discovery makes a heavily pregnant Nancy rethink her choice to marry Esteban. Silas and Doug are successfully managing their dispensary, while Celia is unhappy with her mall job.
After her discovery, Nancy breaks away from Esteban and takes charge of her life again. A deputy is causing some troubles for Doug and Silas. Meanwhile, Celia's way to richness is harder than she thought.
Esteban's other woman threatens Nancy and Esteban's relationship and Nancy reaches out for Andy's help. In the meantime, Dean assists Silas and Doug to set their dispensary back going, but Celia interferes.
Nancy and Andy grow closer together while they try to be good parents. In the meantime, Celia and Dean work together to exploit their product surplus.
With the arrival of new enemies, Shane and Silas needs Nancy's protection. Meanwhile, Andy plans his future with Audra, while Doug and Dean make a plan to put an end to Celia's marijuana business.